Which medication is commonly prescribed for orthostatic hypotension?

Midodrine is commonly prescribed for orthostatic hypotension because it acts as a selective alpha-1 adrenergic agonist. This medication works by causing vasoconstriction, which increases blood pressure, thus helping patients who experience a significant drop in blood pressure upon standing. This condition can result in dizziness, lightheadedness, or even fainting, especially in older adults or individuals with certain medical conditions.

The other medications listed are used for different conditions: Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for pain and inflammation; Pantoprazole is a proton pump inhibitor used for gastroesophageal reflux disease (GERD) and other stomach acid-related conditions; Metformin is an antidiabetic medication used to manage type 2 diabetes. None of these options have the specific mechanism or the intended indication for treating orthostatic hypotension.