What is a significant lifestyle modification that can help prevent gout flares?

Maintaining a healthy weight is a significant lifestyle modification that can help prevent gout flares. Gout is a type of inflammatory arthritis that occurs due to the accumulation of uric acid crystals in the joints, often triggered by hyperuricemia. Excess body weight is a risk factor for developing hyperuricemia, as increased adipose tissue produces more uric acid and often results in decreased renal clearance of uric acid.

By achieving and maintaining a healthy weight, individuals can lower their uric acid levels, thus reducing the risk of gout attacks. This modification is particularly important not just for preventing flares but also for improving overall metabolic health.

In contrast, increased red meat consumption and increased alcohol intake can lead to higher levels of uric acid, thereby increasing the risk of gout flares. Avoiding exercise also negatively affects overall health, including weight management and metabolic processes, and does not contribute to reducing the likelihood of gout attacks.